عرض تفاصيل البحث

ادناه جميع التفاصيل الخاصة بالبحث المطلوب عرضه. توفر هذه المنصة معلومات اساسية حول البحث, لمزيد من التفاصيل يرجى متابعة التصفح من خلال الضغط على الرابط الاصلي للبحث او رابط DOI.

عنوان البحث
Genetic Polymorphisms In Interleukin-17A Were Associated With Typhoid Fever In Babylon City In Iraq
عنوان المجلة
International Journal Of Health Sciences
ISSN-2550-696X
تفاصيل النشر
سنة النشر - 2022 / الفهرس الاصلي للمجلة - 6 : 2 (عدد الصفحات 8)
تصنيف البحث
علوم حياة - المجموعة الطبية
رابط DOI
https://doi.org/10.53730/ijhs.v6nS2.5152
رابط البحث
فتح في موقع المجلة الرسمي
البحث والاستدامة
الهدف 3 – الصحة الجيدة والرفاه   المزيد حول هذا الهدف
البحث والمجتمع
نعم , يدعم
الكلمات المفتاحية
Interleukin-17A, Typhoid Fever, Babylon, Infection

اسم الباحثجهة الانتساببلد الباحث
شيماء جاسم جامعة بابل العراق
زينب فريدحسن جامعة بابل العراق

"Abstract---A total of 50 clinical samples were taken from the blood of typhoid fever patients who visited Al-Hillah Surgical Teaching Hospital and private laboratories in the AL-Hillah/Babylon region between February and August 2021. This research included 50 people who looked to be healthy and disease-free. Genotypes and allele frequency for rs1974226 showed individuals with two T alleles (homozygous for the TT) were significantly represented among the patients with typhoid fever: 14 (28%), P-value = 0.0061, as compared with healthy control subjects, 6 (12%), and had an increased risk of developing typhoid fever infection. The IL-17A (C) allele was less frequent among patients (62%, n =62) than control, and the (T) allele was more frequent among patients than control (38%, n =38). Genotypes and allele frequency for rs1974226 showed individuals with genotype TT were significantly represented among the patients with typhoid fever: 14 (28%), P-value = 0.0061, as compared with healthy control subjects, 6 (12%), and had an increased risk of developing typhoid fever infection. The data has been further examined for each genotype correlated with typhoid fever under different inheritance models. The results showed that there was no significant association between any genotype and typhoid fever under all studies of inheritance models. A highly interesting nucleic acid polymorphism (SNP) was detected in this study in the investigated samples, in which cytosine was replaced with thymine at position 226, namely C226T for the IL-17 gene."