عرض تفاصيل البحث

ادناه جميع التفاصيل الخاصة بالبحث المطلوب عرضه. توفر هذه المنصة معلومات اساسية حول البحث, لمزيد من التفاصيل يرجى متابعة التصفح من خلال الضغط على الرابط الاصلي للبحث او رابط DOI.

عنوان البحث
Effect Of Garlic Nanoparticles On Bone Marrow Function And Antioxidants Status In Experimentally Anemic Male Rats
عنوان المجلة
International Journal Of Health Sciences
ISSN-2550-6978
تفاصيل النشر
سنة النشر - 2022 / الفهرس الاصلي للمجلة - 6 : 6 (عدد الصفحات 15)
تصنيف البحث
علوم حياة - المجموعة الطبية
رابط DOI
https://doi.org/10.53730/ijhs.v6nS6.10099
رابط البحث
فتح في موقع المجلة الرسمي
البحث والاستدامة
الهدف 3 – الصحة الجيدة والرفاه   المزيد حول هذا الهدف
البحث والمجتمع
نعم , يدعم
الكلمات المفتاحية
CNP-G, anemia, bone marrow anatomy, total antioxidant capacity, malondialdehyde.

اسم الباحثجهة الانتساببلد الباحث
حوراء ناجي غضب جامعة القاسم الخضراء العراق
رحاب عيدان كاظم جامعة بابل العراق
حيدر عبد الكاظم جامعة القادسية العراق

Background and Objective: This study was aimed the possibility of using garlic (extract and nanoparticles) in alleviating of bone marrow function and antioxidant status in anemic male rats induced by phenylhydrazine(PHZ). Materials and methods: The CNP-G was prepared according to [1]. Anemia was induced by phenylhydrazine intraperitoneal (20 mg/kg) for 2 consecutive days. A total of 60 adult male albino rats were used in the present study, at the age of 2 months with body weight 195 ± 15gm were divided randomly to six equal groups (10 rats for each) and treated as follows for 8 weeks:- Control group:- in this group animals left without any treatment like negative control.T1: animals in this group was induced anemia and untreated as positive group. T2: animals in this group still normal (no anemic) but treated with daily dose 35.4mg/kg of extract garlic given orally by stomach tube. T3: animals in this group were induced anemia and treated with daily dose 35.4mg/kg of extract garlic given orally by stomach tube. T4: animals in this group still normal (no anemic) but treated with daily dose 35.4mg/kg of CNP-G given orally by stomach tube. T5: animals in this group were induced anemia and treated with daily dose 35.4mg/kg of CNP-G given orally by stomach tube. At the end of the experiment, all animals were sacrificed and blood samples (5ml) were collected directly from the heart by the cardiac puncture. Results: Induction of anemia in rats significantly (P<0.05) decreased red blood cell count (RBC), hemoglobin concentration (Hb), PCV, and total antioxidant capacity . The affect anemic on bone marrow showed by increase adipose tissue within bone marrow. After treatment rats with garlic