عرض تفاصيل البحث

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عنوان البحث
Assessment Ofsimvastatin Effect Andcompare It s Withcombination Of Calcium Plus Vitamin D3 In Postmenopausal Women With Osteoporosis
عنوان المجلة
Medical Journal Of Ahl Al-Bayt University
ISSN-2958-686017
تفاصيل النشر
سنة النشر - 2022 / الفهرس الاصلي للمجلة - 1 : 1 (عدد الصفحات 17)
تصنيف البحث
الصيدلة - المجموعة الطبية
رابط DOI
#
البحث والاستدامة
الهدف 3 – الصحة الجيدة والرفاه   المزيد حول هذا الهدف
البحث والمجتمع
نعم , يدعم

اسم الباحثجهة الانتساببلد الباحث
قيصرجودة فضيل كلية الصيدلة العراق

In osteoporosis, bone strength declines, which increases the chance of bone loss, making it a silent disease. In the elderly, it is the leading cause of bone loss. Forearms, hips, and backbones are among the bones most prone to breaking. There are no symptoms until the bones are destroyed. Bones eventually degenerate to the point that a fracture can occur spontaneously or as a result of simple force. Even after the bone has been destroyed, patients may still experience chronic discomfort and diminished mobility. The goal of this study was to examine the effectiveness of simvastatin with calcium and vitamin D3 in treating osteoporosis in postmenopausal women. Postmenopausal women suffering from bone loss were separated into two groups of twelve women each, with a total of twenty four participants. Twelve postmenopausal women who did not have osteoporosis were included as a control group. Six months of treatment were required. One group took 20mg of simvastatin twice a day, whereas the other took calcium and vitamin D3 (D3 500 I.U. plus 600mg of calcium) twice a day. T-scores, BMD, triglycerides, and total cholesterol were measured in both groups before and after treatment. Patients on simvastatin had significantly higher T-scores than those in the control and calcium + vitamin D3 treatment groups after six months of treatment. After six months of treatment, The simvastatin and calcium + vitamin D3 groups had significantly lower mean serum triglyceride and total cholesterol levels than the control group.